Positions Available

Positions Currently Open

Postdoctoral position in computational cancer metabolomics

University Medical Center has made a major commitment to metabolomics as a critical component to our cancer biology and systems medicine initiatives. A funded position is now available through the NCI T32 Interdisciplinary Program in Tumor Biology at the Lombardi Comprehensive Cancer Center for a computational metabolomics postdoctoral fellow. There are several areas of potential focus including:  1) statistical workflows for genomic-metabolomic cancer data integration; 2) developing informatics pipelines for high-throughput untargeted LC-MS metabolomics; 3) novel computational methods for elucidating stress signal transduction and events at the metabolic level, with particular emphasis on exposure to ionizing radiation and biomarker identification in biofluids and tissues, with extension to microbiome involvement.

Our mass spectrometry facility has assembled state-of-art instrumentation for metabolomics and is a Waters Center of Innovation, with development of untargeted and targeted approaches on LC-MS and LC-TOFMS. GC-MS, NMR, and Seahorse metabolic technologies complement the available platforms.

This metabolomics program is funded to carry out a variety of studies in animal models and patient samples, and the recruit will have opportunities to participate in and build on these projects. Experience in bioinformatics, statistical analysis, and computer programming (R, Python, Java) is required, and background in mass spectrometry, analytical chemistry, and biochemistry will also be taken into consideration. Individuals with excellent communication skills (written and oral), ability to work independently, multitasking and solving problems are encouraged to apply for a position in this dynamic lab.

The current funded position requires U.S. citizenship (or green card). For more details see: http://fornacelab.georgetown.edu

Applicants should send cover letter, resume, and names of references to Dr. A.J.  Fornace Jr at af294@georgetown.edu, Dr. Evagelia C. Laiakis at ecl28@georgetown.edu, and/or Dr. Tytus D. Mak at tdm46@georgetown.edu.

research associate

A research associate position is available in the Metabolomics Shared Resources at Lombardi Comprehensive Cancer Center in Georgetown University for a talented individual with experience in mass spectrometry.  The major focus is qualitative and quantitative analysis of metabolites and other small molecules using Leco Pegasus GC-TOF MS and Waters’ ACQUITY UPLC® QTOF and XEVO TQ-S mass spectrometers. Duties include sample preparation and processing for metabolomics experiments and data analysis and reporting.

Minimum requirements

M.S. in Biochemistry/ Chemistry/Computational Biology or related field

Experience in mass spectrometer operations, method development for small molecule quantitation and MS data analysis preferred.

Desired skills:

Hands on experience in time of flight and triple quadrupole mass spectrometry; strong verbal and written communication skills.

For information contact: af294@georgetown.edu, akc27@georgetown.edu